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Real members of MyChronicPainTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyChronicPainTeam Member asked a question 💭
Borth

Did anyone else taking Venlafaxine become aggressive?
Within 5 days of starting the medication for panic disorder, anxiety and agoraphobia I was shouting at every one. I had no patience (even waiting for a page to load on the computer got me all wound up).
I wanted to fight the world from behind my curtains!

August 18, 2016
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Answer Summary

Members shared mixed experiences with Effexor (Venlafaxine), with several describing increased anger, impatience, and personality changes... Read more

Members shared mixed experiences with Effexor (Venlafaxine), with several describing increased anger, impatience, and personality changes similar to the original poster's experience, while others noted it worked well for them or caused different side effects like depression and withdrawal. Many members emphasized the severe withdrawal symptoms, particularly 'brain zaps' when missing doses, with some taking the medication for years and feeling dependent despite hating it, while others successfully switched to different medications. A recurring theme was the importance of tracking side effects closely, communicating openly with doctors about personality changes or anger, and recognizing that while some people adjust over time, others may need to try different medications to find what works best for their individual needs.

A MyChronicPainTeam Member

You know it is categorized as an antidepressant? Be careful about weight gain. Yes you can become "angry" etc., you may get used to the med and get over it, or you may just need to change to something else. I quit taking that category of med just because of the weight gain. I do, however get angry, periodically, particularly at machines, i.e. the computer taking so long and doing it's own thing instead of what I want it to do. You just have to be aware of it and go to another room or some other distraction to avoid hurting the ones you love. Track your "side effects" and decide if you can control them or if you need to change to something else.

August 22, 2016
A MyChronicPainTeam Member

Interesting I've been on it a few years and I'm angry 24 7 with no patience. I have depression fibromyalgia and borderline personality disorder so I blamed that. But when I switches anti depressant to mertazipine I was even worse.

October 21, 2017
A MyChronicPainTeam Member

The medication can cause personality changes as you found out.

October 16, 2016
A MyChronicPainTeam Member

Can I ask what dosage people are on I will start and take 375mg a day Taking 150 in the morning and 225mg at night I know when i miss a dose. I have been on them for about 10 Years and I bloody HATE THEM

October 16, 2016
A MyChronicPainTeam Member

Yea I had some similar side effects, plus scary heart palpitations.

August 19, 2016

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