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Real members of MyChronicPainTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Has anyone ever heard of/had success with LDN for treating pain?

A MyChronicPainTeam Member asked a question 💭
Laois, Ireland

I’m curious to know has anyone tried this treatment and if so, how have they found it for treating chronic pain.
I know every one is different, but I’m trying to find out what ever I can about it and if people have had positive or negative results with it.
Thank you all xxx

October 4, 2018
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Answer Summary

Members shared mixed experiences and curiosity about LDN (low dose naltrexone) for chronic pain, with several noting that while it has helped... Read more

Members shared mixed experiences and curiosity about LDN (low dose naltrexone) for chronic pain, with several noting that while it has helped some people with fibromyalgia, it often isn't covered by insurance and requires out-of-pocket costs. Many members opened up about their ongoing struggles to find effective pain relief, with one sharing that medical marijuana was the only treatment that provided meaningful relief after nine months of use, while another described long-term use of Cymbalta with uncertain results and expensive brand-name requirements. A recurring theme was the exhausting trial-and-error process of managing chronic pain, the financial barriers to accessing potentially helpful treatments, and the deep need for affordable, accessible options that actually work.

A MyChronicPainTeam Member

Cymbalta
or generic dulexetine is supposed 2 help with pain & depression. I've been on it long-term & I believe it helps. Savella is also supposed 2 help with fibro. Check with doc though as overlapping meds increase similar side effects & can lead 2 serotonin syndrome. I just learned that most serotonin receptors are actually in the gut and not the brain. This was really surprising 2 me. Psych doc told me the gut is like a second brain. I was having a lot of gastrointestinal side effects. He was worried that it was an indication that I had 2 much serotonin in my system. Anyways, that has been my experience so far & sometimes I wonder if it is really the right choice. Everyone reacts differently 2 a med so it's basically trial & error. It feels like I've tried everything out there though. I can only use the brand name on Cymbalta & it is uber expensive. There is a variation of about 15% between different manufacturers & I'm so sensitive that the generic doesn't work for me. Hope this helps. Take care, Chris H

October 26, 2018
A MyChronicPainTeam Member

Low dose naltrexone.

October 29, 2018
A MyChronicPainTeam Member

Making friends with my neighbor upstairs and hanging out with him on the patio.

October 4, 2018
A MyChronicPainTeam Member

Ok i must be really tired of stupid what is LDN?

October 29, 2018
A MyChronicPainTeam Member

Thank you all.
I have been trying to research this myself and had read conflicting information, so its good to hear that it does help for some, always keeping in mind that everyone is different of course!

@A MyChronicPainTeam Member thank you for the links, I will definitely be taking a look. Xxx

October 28, 2018

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