Tofranil (Imipramine) for Chronic Pain

Overview
Tofranil is a prescription drug approved by the Food and Drug Administration (FDA) to treat depression. Tofranil may help manage neuropathic pain. Tofranil is also known by its drug name, Imipramine.

Tofranil is a tricyclic antidepressant. Tofranil is believed to work by changing the balance of neurotransmitters in the brain.

How do I take it?
Tofranil is taken once or twice a day.

Tofranil comes in tablet form.

Side effects
The FDA-approved label for Tofranil lists common side effects including headache, blurred vision, strange dreams, drowsiness, dizziness, dry mouth, nausea, constipation, weight changes, swelling of breasts, and sexual dysfunction.

Rare but serious side effects listed for Tofranil include worsening depression and suicidal thoughts.