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Real members of MyChronicPainTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
Does Anyone Have Experience Of Taking Duloxetine?
A MyChronicPainTeam Member asked a question 💭

I suffer from Chronic Fatigue Syndrome and Fibromyalgia, amongst other things, but I'm in the process of changing over from an antidepressant that I've been taking for 27 years, for anxiety and depression. Im changing from Clomipramine to Duloxetine because Duloxetine, as well as being an antidepressant, apparently helps with chronic pain. I wondered if anyone on here has experience of either, changing over, and/or taking Duloxetine? I'd appreciate any information you can give me. Thank you.

posted July 19, 2016
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A MyChronicPainTeam Member

I used to take Cymbalta and it works wonders for me also! BUT......my insurance stopped covering it and being on disability, I could not afford to pay for it out of pocket. I believe it is a good drug and works very well.

posted August 2, 2016
A MyChronicPainTeam Member

I've been on 60mg of Cymbalta for >3 years and I don't feel like it's doing anything. I was on 120mg but slept all the time.

posted July 26, 2016
A MyChronicPainTeam Member

I changed some years ago as well,from fluoxetine. Was for the same reason. It did not help for the pain or to sleep. But I got better control over panic attacks together with mindfulness . And when I get depressed I do not automatically go into that Downwards spiral to a full depression

posted July 30, 2016
A MyChronicPainTeam Member

I took it for a while. I was on 90mg daily after a period of time. It would help with pain for a bit then stop and the doctor would up my dosage. I was eventually having horrible side effects and feeling like a zombie. I tried to go off of it several times by cutting down and I'd get really sick and dizzy. Lots of people have issues with this medication as I have. I eventually quit cold turkey and after a few weeks I feel so much better as far as the side effects go. I had no idea how many ways it was messing me up until I was off of it. Now my aunt takes it for fibro and loves it, but it was a nightmare med for me. Read up on it. The side effects can get scary. :(

posted July 27, 2016
A MyChronicPainTeam Member

I am taking Cymbalta (duloxetine) for pain and for sleep. I am at the lowest dose and taking 30mg every 3 days at night. I tried taking 30g every day but this was too much for me and had me feeling a bit stoned and unfocused during the day. Taking it every 3 days however has been a miracle for me!!! On the first day after taking it I feel a little sleepy, but on the second and third days my energy is great. Coming from 5 years of suffering, after starting Cymbalta I have had the best weeks of my life since the issues began. It has been helping me a ton but of course it won't work the same for all people.
I was changed from Baclofen to Cymbalta to treat pain without the muscle relaxing side effects. But yes, take it slow and see if a dose works for you! I would definitely recommend trying it out.

posted July 23, 2016 (edited)

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